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While we only implemented ArrayEdit
2018-10-24
While we only implemented ArrayEdit for fluorescence loss and growth rate differences, the method employing HCA is extendable in principle to any image-based phenotype. Phenotypes could be defined by changes in uptake of cytoxicity dyes, live immunocytochemistry for cell surface or extracellular mat
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cyproheptadine hcl manufacturer Small or immature teratomas
2018-10-24
Small or immature teratomas are particularly hard to detect due to the lack of tissues with high secretion levels such as gland-like structures. In line with that, we found one teratoma in our test set for which none of the eight tested biomarkers was positive. Histological characterization showed t
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Because the process of dedifferentiation through
2018-10-24
Because the process of dedifferentiation through the addition of Yamanaka factors is extremely inefficient, the actual contribution of de novo generated “CSC states” via oncometabolic reprogramming to cancer evolution might be a matter of conjecture. To evaluate such a situation, we first confirmed
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mSSCs can be maintained and genetically manipulated in
2018-10-24
mSSCs can be maintained and genetically manipulated in vitro over extensive periods, providing a valuable resource for in vitro studies of meiosis and post-meiotic development (Kanatsu-Shinohara et al., 2003; Kubota et al., 2004). In the past decade, this culture system has been used to identify key
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br Results br Discussion Human HLCs
2018-10-24
Results Discussion Human HLCs derived from pluripotent stem Angiogenesis Compound Library are permissive to infection by hepatotropic viruses, including HCV and HBV. Interestingly, the SEC14L2 gene, an essential host factor for supporting the replication of wild-type, unadapted HCV genomes, w
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Alzheimer s disease AD is the
2018-10-24
Alzheimer\'s disease (AD) is the most common neurodegenerative disorder. The pathological hallmarks of AD include extracellular amyloid plaques consisting mainly of Aβ42, and intracellular neurofibrillary tangles comprising mainly hyperphosphorylated tau (Serrano-Pozo et al., 2011). Previous studies
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Such spontaneous Ca transients have
2018-10-24
Such spontaneous Ca2+ transients have been reported in postnatal mouse cochlear supporting cells (Tritsch et al., 2007), and the Ca2+ signals were suggested to be propagated via gap junctions and hemichannels containing CX26 and CX30 (Anselmi et al., 2008; Schutz et al., 2010). It was also suggested
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The transient presence of oligodendroblasts
2018-10-24
The transient presence of oligodendroblasts could also be explained by their progress into full maturation. Intriguingly, we failed to detect fully mature oligodendrocytes generated by oligodendroblasts. This was determined in three ways: first, by the absence of double EYFP+/MBP+ cells; second, by
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br Discussion hESCs provide an extraordinary platform for
2018-10-24
Discussion hESCs provide an extraordinary platform for disease modeling, especially for developmental disorders (Avior et al., 2016). We decided to use their unique characteristics to model developmental and tumorigenic aspects of pRB and TRb, a severe neonatal malignancy. Using gene editing, we
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br After quantization the Laplace Beltrami operator where re
2018-10-24
After quantization, the Laplace-Beltrami operator where , replaces the quadratic form of the momenta (11). In this case, the “kinetic energy” operator has the form The first term in (14) is a “radial” part of the kinetic energy of the Universe similar to the radial part of the kinetic energy
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br Deposition of MgSe thin films MgSe thin solid films
2018-10-24
Deposition of MgSe thin films MgSe thin solid films were prepared using the versatile spray pyrolysis technique, which is simple and economic as compared to the MBE and MOCVD methods. The properties of the film can be controlled by adjusting the preparative parameters such as substrate temperatur
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As a comparison Fig d
2018-10-24
As a comparison, Fig. 2d shows the shape of the curve for the probe approaching the measured sample (curve 2) for the case when the standard system for detecting the position of the probe tip is used. This system is based on the principle of registering the position of the laser beam reflected from
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where and are the effective densities of states of electrons
2018-10-24
where and are the effective densities of states of electrons and holes in a two-dimensional subband, respectively; Let us assume that the equality is satisfied under optical excitation, and find the dependence of the position of the quasi Fermi levels of electrons and holes on the temperature and
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br Introduction The obesity epidemic has
2018-10-24
Introduction The obesity epidemic has been linked to a web of interdependent causes operating at multiple cascading levels (Galea, Riddle, & Kaplan, 2010; Glass & McAtee, 2006; Huang, Drewnosksi, Kumanyika, & Glass, 2009) including environmental influences, genetics, cultural preferences, environ
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br Results br Discussion br Conclusion br Acknowledgements
2018-10-24
Results Discussion Conclusion Acknowledgements This study was supported by a grant from the Norwegian Research Council (Grant no. 190709 (FRIPRO)). It is not under consideration for publication elsewhere. A licensure to match data to undertake this study was provided by the National Data
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