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We also find that PRKCZ fails
2018-11-02
We also find that PRKCZ fails to accumulate normally at the apical membrane in Gata3 mutant embryos, even though its expression and activation levels are maintained. PRKCZ is part of the apical Par complex comprising PARD3 and PARD6B and acts as a key regulator of mitotic spindle orientation in othe
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The electrostatic spectrographs are not
2018-11-02
The electrostatic spectrographs are not yet industrially manufactured and the devices proposed are rather the experimental models (see Refs. [2, 4–6]). A theory for designing potential structures where the spectrographic mode is implemented has been developed at our Laboratory of Corpuscular Optic
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br Acknowledgment The study has been
2018-11-02
Acknowledgment The study has been conducted with the support of the Russian Science Foundation (Contract no. 14-29-00178). Introduction Hydrogen embrittlement is the reason for numerous catastrophes, so its mechanisms are thoroughly studied [1–6]. The emergence and movement of dislocations a
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br Objects and methods of
2018-11-02
Objects and methods of study The PE samples were acted upon two types of effects: The angular shift of (002) reflection patterns to smaller angles was recorded upon elastic tensile stress at T = 90 K by X-ray diffractometry. The increase of the distance between the skeletal carbon atoms along
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The morphological features of the MnO modified materials obt
2018-11-02
The morphological features of the MnO2-modified materials obtained are clearly visible in Figs. 2 and 3 which show the surfaces of these materials, imaged by SEM at different magnifications. It can be seen that high-silica samples (see Fig. 2a) have a monolithic structure, apparently consisting of c
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br Previous research on informal care
2018-11-02
Previous research on informal care provision and health Previous studies exploring the link between provision of informal care and health reflect the complexity of researching this topic area. Cross-sectional analyses may be limited in examining the factors preceding or following an individual\'s
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br Statistical analyses We estimate one model for each
2018-11-02
Statistical analyses We estimate one model for each health outcome. For the physical markers of health, as well as self-rated health we estimate model 1, while for the health behaviour outcomes we estimate model 2:where Y is the outcome variable; MAB is the maternal age at the time of birth for t
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OAs can be divided into two groups
2018-11-01
OAs can be divided into two groups: mandibular advancement devices (MADs), which are attached to the teeth and move the mandible anteriorly, and tongue retaining devices, which use suction to position the tongue anteriorly inside a bulb [5]. MADs have higher success and compliance rates than tongue
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When the capacitor was connected to the Al
2018-11-01
When the capacitor was connected to the Al/phosphate cell via a switch capacitor regulator circuit and was charged from 1.4V to 1.8V, the charging times were 0.51±0.02s and 0.34±0.03s for the single cell and the 2-cell configuration, respectively (Fig. 5). The charge/discharge cycle was observed app
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br Materials and methods br Results br
2018-11-01
Materials and methods Results Discussion Discovery and characterization of cancer-associated markers effective in cancer diagnosis and treatment is a main focus in modern medicine. Several targets have been described [13,14]. Furthermore, we recently showed that the malarial VAR2CSA protein
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Por su parte la tr
2018-11-01
Por su parte, la tríada gdw mostró muy poco conocimiento de la “Base Industrial de la Defensa” y de cómo el proceso de contratación del Pentágono se interconecta con esta base. Entonces, no es ninguna sorpresa que gdw hayan encontrado que las fluctuaciones en el gasto público militar no explican en
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br Funding Association Fran aise contre les Myopathies AFM
2018-11-01
Funding Association Française contre les Myopathies (AFM-Téléthon), French National Health Institute (INSERM), French National Research Agency (ANR), Bettencourt-Schueller Foundation, Cognacq Jay Foundation, Fondamental Foundation, Servier Laboratories. Role of the Funding Sources Aknowledg
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The nuclear factor one NF family consists of four site
2018-11-01
The nuclear factor one (NF1) family consists of four site-specific transcription factors (NfiA, NfiB, NfiC, and NfiX) that play a large role in the development of a number of organs systems such as the lung and Senexin B (Grunder et al., 2002; Harris et al., 2015; Hsu et al., 2011; Steele-Perkins e
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Serum phenylacetylglutamine and hydroxyphenylacetylglutamine
2018-11-01
Serum phenylacetylglutamine and 4-hydroxyphenylacetylglutamine, which provide a major route of excretion of excess nitrogen from the body, were elevated in children with EED. Phenylacetylglutamine is formed from the conjugation of phenylacetate (from the gut microbiome or host) and glutamine (mainly
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Translational approaches to targeting the biological basis
2018-11-01
Translational approaches to targeting the biological basis of aging is a rapidly-developing field. discuss targeting cellular senescence programs to improve fitness. Among these approaches are so-called senolytic agents, which selectively clear senescent GSK-J1 sodium salt and relieve the associat
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